Coastal Pediatric Associates Coastal Pediatric Associates


Atopic Dermatitis in Babies and Children

According to the American Academy of Pediatrics at least one in 10 children has atopic dermatitis (also called eczema), an ongoing skin problem that causes dry, red, itchy skin. Children with eczema have more sensitive skin than other people, and here's what parents need to know about the condition. 


Problems with the skin barrier cause atopic dermatitis in children; often, kids do not have enough of a particular protein called "filaggrin" in the outer layer of the skin. Filaggrin helps skin form a strong barrier between the body and the environment. Skin with too little of this protein has a more challenging time holding in water and keeping out bacteria and environmental irritants. Both a person's genes and environment play a role in this condition. 


Atopic dermatitis rashes can be different for each child and can be all over the body or in just a few spots. The rash often worsens at times and then gets better. Where the rashes develop may change over time: 

  • In babies, eczema usually starts on the scalp and face. Red, dry rashes may show up on the cheeks, forehead, and around the mouth. Eczema usually does not develop in the diaper area. 
  • In young school-aged children, the eczema rash is often in the elbow creases, on the backs of the knees, on the neck, and around the eyes. 


Atopic dermatitis can be frustrating for children and their parents, especially when the itching makes it challenging to sleep. Your pediatrician can help you manage your child's eczema symptoms with a treatment plan and a healthy skin maintenance routine. 


If your child has been diagnosed with atopic dermatitis, we are currently enrolling in a treatment study for children ages 2-17 years old. You can learn more about this study by calling 843-473-6523 or visiting You can also email us at to see if your child is eligible for this study.  



From Clinical Trials to Helping Future Generations

Participation in research and clinical trials is essential in discovering better and more innovative ways to deliver care that improves outcomes.  When your child participates in a clinical trial, the information collected helps researchers understand new treatments. A great example of this is the rollout of the COVID-19 vaccine to children ages 5-11. This new treatment may help protect your child and other children from getting COVID-19 and therefore reduce their risk of severe disease, hospitalizations, or developing long-term COVID-19 complications in many. Without clinical trials, this option would not be available today.  


The researchers at Coastal Pediatric Research strive to remain at the forefront of medical care, going above and beyond to provide your family with the best care possible.  We believe the most exciting aspect of research isn’t just helping our families and patients who participate in trials today, but the ability to benefit all children we treat, today and in the future. Our research team is here to walk you through each study, answer your questions and find the opportunity that best fits your needs.


If you would like to participate in a clinical trial or learn more about how you can help future generations, please visit



Why is Clinical Research in Children Essential?

It's essential to study new treatments in children because children are not little adults. Children have different treatment needs than adults, and sometimes they have other diseases than adults. Also, doses of medicine, sizes of devices, or types of therapy may change over time according to each child's needs and stage of growth and as more information about the side effects and usefulness of a drug becomes available over time.


A successful clinical trial can create a new standard of care for children with certain conditions. Without a standard of care for children with certain conditions, treatment for children may need to be based on what works for adults. For example, most medicines given to children as part of standard treatments have only been tested in adults. When medicine that has been tested only in adults is given to children, this is called off-label use of the medicine.


In recent years, laws have been passed that require pediatric clinical trials for specific conditions. As a result, the number and range of clinical trials for children have expanded. Each clinical trial follows a detailed plan called a protocol. A protocol is carefully designed to minimize the study's risks, increase the chance of getting useful results, and answer specific research questions. It includes a description of who can and cannot participate, the likely length of the study, information about what is being tested, and how the information will be collected. Before clinical trials of new medicines begin, these medicines are first tested and studied in a laboratory and in animals.?


Source: Healthy Children by the American Academy of Pediatrics